Job Description

Job Description

Job Description

Who We Are

EvolveImmune Therapeutics is a next-generation, development-stage immune-oncology company which is developing novel trispecific T cell engagers with integrated CD2 costimulation to optimize anti-tumor immunity to overcome the therapeutic challenges of cancer cell resistance. Our lead program based on our EVOLVE therapeutic platform will enter the clinic in 2025. We conduct our R&D, including internal protein engineering and biotherapeutics discovery, immunobiology, and translational sciences, at our dedicated, state-of-the-art laboratories located in Branford, CT.

The Role

We are seeking an ambitious and technically strong scientist with strong attention to experimental details, who is eager to establish a career in biotechnology, enjoys working in a team, and can leverage the growth opportunities provided by a matrixed environment. Candidates with basic cell biology laboratory experience, animal handling skills, and in vivo procedure experience are preferred. This is an exceptional opportunity for someone passionate about drug discovery and driven to translate discoveries into novel therapeutics.

EvolveImmune has identified development candidates that are rapidly advancing toward IND filing and first-in-patient trials. The EvolveImmune team moved into a custom-built, 7,000+ square foot lab space in Branford, CT, in October 2020 and recently expanded their footprint to over 16,000 square feet of newly renovated lab space to support therapeutic development and clinical translation of programs advancing to the clinic.

Responsibilities

• Maintain and expand various cancer cell lines using sterile tissue culture techniques and according to study protocols and timelines to support in vivo studies.
• Train with head of in vivo pharmacology and team members to support procedures required to stage and execute in vivo studies in approved IACUC procedures and guidelines.
• Assist with in vivo tumor cell engraftment, adoptive immune cell transfer, and blood and tissue harvest for cell, RNA and protein profiling.
• Assist with drug administration by intraperitoneal (IP), Intratracheal (IT), intranasal (IN) and tail intravenous (IV) routes.
• Perform in vivo measurements that include mouse body weight and Caliper-based tumor volume measurements.
• Keep detailed records of experiments in electronic notebooks, analyze data and prepare and deliver presentations to research team members.

Qualifications and Experience

• B.S./B.A. degree in biology or a related field, with 3+ years of cell biology laboratory skills and experience.

This role is a full time, in-person position in EvolveImmune's laboratories in Branford, CT. Candidates must have the with the ability to travel to Farmington, CT site when necessary is required.

EvolveImmune Therapeutics requires all employees to be fully vaccinated against COVID-19. You may seek reasonable accommodations for medical and religious reasons. However, your application is no guarantee that such accommodations will be made available.

EvolveImmune will provide a competitive compensation package based on the candidate's experience level.

EvolveImmune Therapeutics, Inc. is an equal opportunity employer.

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